| 发明名称 |
METHODS FOR PURIFYING HIGHLY ANIONIC PROTEINS |
| 摘要 |
The present invention provides a process for isolating and purifying highly anionic target proteins, for example, sulfated proteins. Sulfated proteins have five or more, sulfations. In a preferred embodiment, the sulfated protein has six sulfations, e.g., six sulfations on N-terminal tyrosine residues, as embodied in PSGL-1 (P-selectin glycoprotein ligand).
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| 申请公布号 |
WO0172769(A9) |
申请公布日期 |
2003.04.03 |
| 申请号 |
WO2001US09815 |
申请日期 |
2001.03.27 |
| 申请人 |
GENETICS INSTITUTE, LLC |
发明人 |
COFFMAN, JONATHAN, L.;FOSTER, WILLIAM, BARRY;GERMAIN, BONNIE, J.;SUN, SHUJUN;ROBINSON, JEFFREY, J. |
| 分类号 |
C07K14/00;C07K1/14;C07K1/18;C07K1/20;C07K14/705;C07K19/00;(IPC1-7):C07K1/18 |
主分类号 |
C07K14/00 |
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