METHOD FOR THE DETECTION OF CYTOCHROME B MUTATIONS IN FUNGI
摘要
This invention relates to disgnostic methods for the detection of one or more cytochrome b mutations in fungi at the position corresponding to Saccharomyces cerevisiae cytochrome b residue 129 that leads to resistance to strobilurin analogues or compounds in the same cross resistance group using any (or a) single nucleotide polymorphism detection technique, preferably using either an allele specific amplification technique such as the amplification refractory mutation system (ARMS) or preferably using an allele selective hybridisation probe technique such as Molecular Beacons or TaqMan. The invention also relates to mutation specific oligonucleotides for use in the method and to diagnostic kits containing these oligonucleotides.
申请公布号
WO02081742(A3)
申请公布日期
2003.04.03
申请号
WO2002GB01411
申请日期
2002.03.25
申请人
SYNGENTA LIMITED;BURBIDGE, JUDITH, MARY;CLEERE, SALLY, MICHELE;STANGER, CAROLE, PATRICIA;WINDASS, JOHN, DAVID
发明人
BURBIDGE, JUDITH, MARY;CLEERE, SALLY, MICHELE;STANGER, CAROLE, PATRICIA;WINDASS, JOHN, DAVID