发明名称 SYNTHESIS AND EVALUATION OF NOVEL PHTHALIMIDE MIMICS AS ANTI-ANGIOGENIC AGENTS
摘要 The present invention is directed to novel thalidomide derivative compounds that have activity as anti-angiogenic compounds. More particularly the compounds have the general structure: where R1 is selected from the group consisting of H, halo, alkyl, haloalkyl, -NH2, hydroxy and alkoxy; R2 is selected from the group consisting of optionally substituted bicyclic, optionally substituted aryl, and R6 is H, or C1-C8 alkyl; R19 is optionally substituted aryl; and m is 0-6.
申请公布号 WO02086078(A3) 申请公布日期 2003.04.03
申请号 WO2002US12655 申请日期 2002.04.22
申请人 UNIVERSITY OF VIRGINIA PATENT FOUNDATION;BROWN, MILTON, L. 发明人 BROWN, MILTON, L.
分类号 A61K31/395;A61K31/4035;A61K31/437;A61K31/472;A61K31/4725;A61K31/517;A61K31/55;A61P3/02;A61P3/10;A61P7/06;A61P9/00;A61P15/18;A61P17/00;A61P17/02;A61P19/02;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/10;A61P31/22;A61P33/00;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D209/48;C07D217/24;C07D223/16;C07D225/06;C07D239/91;C07D401/04;C07D405/04;C07D471/04 主分类号 A61K31/395
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