TREATMENT OF TUMORS WITH ACETYLENES DISTRIBUTED WITH A PHENYL OR HETEROAROMATIC GROUP AND A SUBSTITUTED CHROMANYL, THIOCHROMANYL OR TETRAHYDROQUINOLINYL GROUP IN COMBINATION WITH OTHER ANTI-TUMOR AGENTS

摘要

Compounds of the Formula (1) where the symbols have the meaning described in the specification, and particularly the compound of the Formula (3) exhibit synergistic anti-proliferative effect with human recombinant interferon in the treatment of solid tumors and leukemia, particularly breast cancer and acute myeloid leukemia.