发明名称 |
MODIFIED RELEASE DOSAGE FORMS |
摘要 |
A dosage form comprises: (a) at least one active ingredient: (b) a core having a first surface portion upon which resides a first coating and a second surface portion which is substantially free of the first coating; and (c) a shell which resides upon at least a portion of the second surface portion, wherein the shell comprises a different material from the first coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b)a core comprising a center portion having an exterior surface and an annular portion having an exterior surface and an interior surface, wherein the annular portion interior surface is in contact with at least a portion of the center portion exterior surface, and a coating resides on at least a portion of the annular portion exterior surface; and (c) a shell which resides upon at least a portion of the exterior surface of the center portion, wherein the shell comprises a different material than the impermeable coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core having an outer surface and a cavity which extends at least partially through the core such that the core outer surface has at least a first opening therein; (c) a first coating which resides on at least a portion of the core outer surface, wherein the first shell portion comprises a different material from the first coating; and (d) a first shell portion which is adjacent to the first opening and covers at least the first opening. |
申请公布号 |
WO03026629(A2) |
申请公布日期 |
2003.04.03 |
申请号 |
WO2002US31117 |
申请日期 |
2002.09.28 |
申请人 |
MCNEIL-PPC, INC.;LEE, DER-YANG;LI, SHUN-POR;SOWDEN, HARRY, S.;THOMAS, MARTIN;WYNN, DAVID |
发明人 |
LEE, DER-YANG;LI, SHUN-POR;SOWDEN, HARRY, S.;THOMAS, MARTIN;WYNN, DAVID |
分类号 |
A23G3/34;A23G1/00;A23G1/54;A23G3/00;A23G3/04;A23G3/36;A23G3/54;A23L1/00;A23L1/09;A23L1/30;A61J3/00;A61J3/06;A61J3/10;A61K9/00;A61K9/14;A61K9/20;A61K9/22;A61K9/24;A61K9/26;A61K9/28;A61K9/30;A61K9/32;A61K9/34;A61K9/36;A61K9/38;A61K9/48;A61K9/50;A61K31/136;A61K31/137;A61K31/277;A61K47/10;A61K47/14;A61K47/26;A61K47/30;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/44;A61K47/46;A61P11/00;B30B11/08;B30B11/34;B30B15/30;G06F17/30 |
主分类号 |
A23G3/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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