| 发明名称 |
ENZYME PHOSPHORYLATING Ser46 of p53 |
| 摘要 |
PROBLEM TO BE SOLVED: To obtain an entirely new enzyme by elucidating an enzyme phosphorylating a serine residue of the 46th amino acid of p53 and further elucidating a control mechanism of an apoptosis induction ability of the p53. SOLUTION: This enzyme phosphorylating the Ser46 of the p53 is completely purified to elucidate what the enzyme is. That is, the enzyme composed of casein kinase 2 and p53 damage inducible nuclear protein 1 (p53DINP1) is provided.
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| 申请公布号 |
JP2003093056(A) |
申请公布日期 |
2003.04.02 |
| 申请号 |
JP20010292953 |
申请日期 |
2001.09.26 |
| 申请人 |
JAPAN SCIENCE & TECHNOLOGY CORP;NATIONAL CANCER CENTER-JAPAN |
发明人 |
TAYA YOICHI;TANAKA TOMOAKI;NAKAMURA YUSUKE;ARAKAWA HIROBUMI |
| 分类号 |
G01N33/50;A61K38/00;A61K38/45;A61P35/00;C07K14/47;C12N9/12;C12Q1/48;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12N9/12 |
主分类号 |
G01N33/50 |
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