| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing (S)-3-quinuclidinol useful as an intermediate of physiologically active substances (e.g. medicaments). SOLUTION: This method for producing the (S)-3-quinuclidinol comprises making an enzyme (a) or (b) act on 3-quinuclidinone or a salt thereof, wherein the enzyme (a) is an enzyme having a specific amino acid sequence, and the enzyme (b) is an enzyme having an amino acid sequence where one or several amino acid(s) are deleted, substituted or added from/for/to the amino acid sequence in the enzyme (a) and also having the enzymatic activity of reducing 3-quinuclidinone into the objective (S)-3-quinuclidinol.
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