发明名称 |
GEMCITABINE DERIVATIVES |
摘要 |
The invention provides Gemcitabine esters or amides in which the 3'- and/or 5'-OH group and/or the N4-amino group is derivatised with a C18- and/or C20-saturated or mono-unsaturated acyl group, preferably an acyl group selected from oleoyl, elaidoyl, cis-eicosenoyl and trans-eicosenoyl. The Gemcitabine esters and amides are useful as anti-cancer and anti-viral agents. |
申请公布号 |
EP0986570(B1) |
申请公布日期 |
2003.04.02 |
申请号 |
EP19980901592 |
申请日期 |
1998.01.23 |
申请人 |
CONPHARMA AS |
发明人 |
MYHREN, FINN;BORRETZEN, BERNT;DALEN, ARE;SANDVOLD, MARIT, LILAND |
分类号 |
C07H19/073;A61K31/7068;A61P31/12;A61P35/00;C07H1/00;C07H19/06 |
主分类号 |
C07H19/073 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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