Novel stable crystal of thiazolidinedione derivative and process for producing the same

摘要

A homogeneous crystal having excellent stability which is suitable for the industrial-scale production of 5-Ä(2,4-dioxothiazolidin-5-yl)methylÜ-2-methoxy-N-ÄÄ4-(trifluoromethyl )phenylÜmethylÜbenzamide (KRP-297). The novel crystal of KRP-297 is produced through recrystallization from an alcohol solvent. It is characterized by having diffraction angles (2θ) at at least 9.7 DEG , 15.0 DEG , and 22.5 DEG in X-ray powder diffractometry.