摘要 |
Disclosed are benzonaphthyridines of general formula (I), wherein R1 is C1-4-alkyl, R is hydroxyl, C1-4-alkoxy, C3-7-cycloalkoxy, C3-7-cycloalkylmethoxy or C1-4-alkoxy, which is completely or mostly substituted by fluorine, R3 is hydroxyl, C1-4-alkoxy, C3-7-cycloalkoxy, C3-7-cycloalkylmethoxy or C1-4-alkoxy, which is completely or mostly substituted by fluorine or wherein R2 and R3 together create the group C1-2-alkylenedioxy, R4 is phenyl radical, which is substituted by the group R5 and R6, the meaning of which is indicated in the description, pharmaceutical composition containing them and their use for bronchial or therapeutics. |