发明名称 |
Mammalian IAP gene family, primers, probes and detection methods |
摘要 |
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP-family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
|
申请公布号 |
US6541457(B2) |
申请公布日期 |
2003.04.01 |
申请号 |
US19980201936 |
申请日期 |
1998.12.01 |
申请人 |
AEGERA THERAPEUTICS INC. |
发明人 |
KORNELUK ROBERT G.;MACKENZIE ALEXANDER E.;BAIRD STEPHEN;LISTON PETER |
分类号 |
A01K67/027;A61K31/00;A61K38/00;A61K39/395;A61K48/00;A61P1/00;A61P1/16;A61P9/00;A61P9/10;A61P25/00;A61P31/00;A61P31/18;A61P43/00;C07K14/47;C07K16/18;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/68;C12R1/91;G01N33/15;G01N33/50;G01N33/53;G01N33/566;(IPC1-7):A61K48/00;C12N5/00 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|