Methods for preparing coated drug particles useful for treating respiratory disorders or pulmonary infections

摘要

A medicament comprises a plurality of coated drug particles with each particle having an average particle size of less than 500 mm in diameter. The surface of the particles comprises at least a first layer of biodegradable and biocompatible polymeric coating particles. The average thickness of the coating layer is between 1 and 500 nm and the coated particles are obtained through depositing the polymeric coating particles onto the surface of the host drug particle by a process of pulsed laser ablation. The medicament can be used to treat a respiratory disorder or pulmonary infection.