发明名称 |
Selective reduction of alkyne compounds |
摘要 |
A process is provided for the preparation of cyclohexene derivatives of general formula I or II: in which the substituents R1 and R2 independently of one another are defined as follows: R2 is OH or a protective group convertible to a hydroxyl group by hydrolysis, R3 and R4 are hydrogen or C1-C4-alkyl, and R5 is hydrogen or C1-C4-acyl, by the reduction or alkyne compounds of general formula III or IV: wherein the reducing agent used is at least one salt of hyposulfurous acid or hydroxymethanesulfinic acid or a mixture of at least one salt of hyposulfurous acid and at least one salt of hydroxymethanesulfinic acid.
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申请公布号 |
US2003060639(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
US20020217488 |
申请日期 |
2002.08.14 |
申请人 |
GRIMMER JOHANNES;MULLER THOMAS;BOMM VOLKER |
发明人 |
GRIMMER JOHANNES;MULLER THOMAS;BOMM VOLKER |
分类号 |
C07B35/02;C07C45/62;C07C49/713;C07C49/743;C07C403/02;C07C403/08;C07D317/44;C07D317/46;C07D317/50;C07D317/64;(IPC1-7):C07D317/46 |
主分类号 |
C07B35/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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