发明名称 |
Netrin receptors |
摘要 |
The invention provides methods and compositions relating to vertebrate UNC-5 proteins which function as receptor proteins for netrins, a family of cell guidance proteins. The proteins may be produced recombinantly from transformed host cells from the disclosed vertebrate UNC-5 encoding nucleic acid or purified from human cells. The invention provides specific hybridization probes and primers capable of specifically hybridizing with the disclosed vertebrate unc-5 gene, vertebrate UNC-5-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
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申请公布号 |
US2003059859(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
US20020256702 |
申请日期 |
2002.09.27 |
申请人 |
TESSIER-LAVIGNE MARC;LEONARDO E. DAVID;HINCK LINDSAY;MASU MASAYUKI;KEINO-MASU KAZUKO |
发明人 |
TESSIER-LAVIGNE MARC;LEONARDO E. DAVID;HINCK LINDSAY;MASU MASAYUKI;KEINO-MASU KAZUKO |
分类号 |
G01N33/50;A61K31/7088;A61K39/00;A61K39/395;A61K45/00;A61K48/00;A61P25/00;C07K1/00;C07K14/00;C07K14/705;C07K14/71;C07K16/28;C07K17/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;G01N33/15;G01N33/53;G01N33/566;G01N33/68;(IPC1-7):G01N33/53;G01N33/567;C07K16/40 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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