发明名称 |
NEUROPROTECTION AFTER TRAUMATIC BRAIN INJURY |
摘要 |
The invention provides compositions and methods for treating traumatic brain injury by the administration of a noncompetitive AMPA receptor antagonist. In certain embodiments, the noncompetitive AMPA receptor antagonist is a 2,3-benzodiazepine derivative. Illustrative 2,3-benzodiazepine derivatives useful according to the invention include (R)-7-acetyl-5(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3] benzodiazepine.
|
申请公布号 |
WO03024458(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
WO2002US29512 |
申请日期 |
2002.09.18 |
申请人 |
IVAX INSTITUTE FOR DRUG RESEARCH, INC. |
发明人 |
BELAYEV, LUDMILA;GINSBERG, MYRON, D. |
分类号 |
A61K31/551;(IPC1-7):A61K31/551 |
主分类号 |
A61K31/551 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|