发明名称 |
Method and biosensor for analysis |
摘要 |
In a method for analysis biomolecules (3) attached to a solid surface of a substrate (1) are used for detecting the presence of analytes (4) in a sample by binding of the analytes to the biomolecules. The biomolecules (3) are attached directly to the surface of the substrate together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent nonspecific binding of analytes (4) and other biomolecules. The invention relates also to a biosensor where biomolecules (3) are attached directly to the substrate (1) together with biomolecule-repellent molecules (5), which cover the surface between the biomolecules (3) to prevent non-specific binding of analytes (4) and other biomolecules. The biomolecules (5) can be self-assembled hydrophilic polymers. One example of using the invention is immunological analysis using surface plasmon resonance (SPR).
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申请公布号 |
US2003059954(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
US20020164652 |
申请日期 |
2002.06.10 |
申请人 |
VIKHOLM INGER;SADOWSKI JANUSZ |
发明人 |
VIKHOLM INGER;SADOWSKI JANUSZ |
分类号 |
G01N5/02;G01N21/27;G01N33/543;(IPC1-7):G01N33/543 |
主分类号 |
G01N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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