| 摘要 |
Compounds of the general formula (I), their optical isomers or prodrugs, pharmaceutically acceptable salts of the compounds, the isomers, or the prodrugs, or solvates of the same; and metalloprotease inhibitors containing the compounds, the optical isomers, the prodrugs, the salts, or the solvates : (I) wherein R1 is hydroxyl or the like; R2 is optionally substituted lower alkyl or the like; R3 is hydrogen or the like; R4 is optionally substituted arylene or the like; R5 is a group of formula (II) or (III): (III) and R6 is optionally substituted aryl or the like.
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