AMINO ACID MODULATED EXTENDED RELEASE DOSAGE FORM

摘要

Disclosed herein is an oral extended release dosage form, such as a tablet, comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extragranular polymer matrix which is more rapidly hydrating than the intragranular polymer. The amino acid is selected for hydropathy characteristics depending on solubility characteristic of the active compoun d.