发明名称 |
Novel clot-specific steptokinase proteins possessing altered plasminogen activation characteristics and a process for the preparation of said proteins |
摘要 |
Clot-specific streptokinase proteins possessing altered plasminogen characteristics, including enhanced fibrin selectivity. The kinetics of plasminogen activation by these proteins are distinct from those of natural streptokinase, in that there is a temporary delay or lag in the initial rate of catalytic conversion of plasminogen to plasmin. Also disclosed are processes for preparing the proteins.
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申请公布号 |
US2003059921(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
US20010940235 |
申请日期 |
2001.08.27 |
申请人 |
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH OF RAFI MARG, A NEW DELHI, INDIA CORPORATION |
发明人 |
SAHNI GIRISH;KUMAR RAJESH;ROY CHAITI;RAJAGOPAL KAMMARA;NIHALANI DEEPAK;SUNDARAM VASUDHA;YADAV MAHAVIR |
分类号 |
A61K38/00;C07H21/04;C07K14/315;C07K14/78;C07K19/00;C12N1/21;C12N9/12;C12N9/70;C12N15/58;C12Q1/68;(IPC1-7):C12N9/64;C12P21/02;C12N5/06 |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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