| 摘要 |
The present invention provides vectors that encode single-chain antigen-binding units in both prokaryotic and eukaryotic cells. The vectors are particularly useful for generating a genetically diverse repertoire of single-chain antigen-binding units to facilitate an in vivo screening of antigen-binding units that bind to a desired antigen inside a cell. The present invention also provides recombinant polynucleotides, host cells and kits comprising the vectors. Further provided by the invention are methods of using the subject vectors.
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