摘要 |
<p>A method is disclosed for increasing the production of an enzyme by a microorganism. The method comprises placing a microorganism that produces an enzyme into a medium that supports growth of the microorganism, and applying an electrical current to the medium to introduce electrons into the medium. The method produces higher enzyme titer at a higher productivity. In other words, the amount of the enzyme produced b the microorganism in a time period using the method is greater than a second amount that would be produced by the microorganism in the same time period when no electrical current is applied to the medium. The method may be practiced in an electrochemical bioreactor, and in example embodiments, the method increases the rate and amount of hydrolytic enzyme (e.g., cellulase and collagenase) production for specific bacteria (e.g., bacteria selected from the genera Clostridium, Bacteroides, Ruminococcus, Micromonospora and Acetivibrio).</p> |