发明名称 ABERRANT GLUTAMATE TRANSPORTERS AND METHODS OF USE
摘要 In one aspect, the present invention features methods for detecting at least one neurological disorder in a patient, the method comprising obtaining a biological sample from the patient; and detecting at least one aberrant human glutamate transporter 2 (EAAT 2) mRNA in the sample as being indicative of the neurological disorder in the patient. In a particular aspect, the invention is useful for detecting amyotrophic lateral sclerosis (ALS) in the patient.
申请公布号 US2003060617(A1) 申请公布日期 2003.03.27
申请号 US19980040736 申请日期 1998.03.18
申请人 LIN CHIENG-LIANG GLENN;BRISTOL LYNN A.;ROTHSTEIN JEFFERY D. 发明人 LIN CHIENG-LIANG GLENN;BRISTOL LYNN A.;ROTHSTEIN JEFFERY D.
分类号 C12Q1/68;(IPC1-7):G01N33/53;A01N43/04;A61K31/70;C07H21/02;C07H21/04;C12N1/20;C12N15/00;C12N15/09;C12N15/63;C12N15/70 主分类号 C12Q1/68
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