POLYMORPHISMS IN A DIACYLGLYCEROL ACYLTRANSFERASE GENE, AND METHODS OF USE THEREOF
摘要
The present invention provides isolated an polynucleotide comprising a polymorphic nucleotide sequences from a diacylglycerol acyltransferase (DGAT) gene, wherein at least one a polymorphism is associated with a condition relating to DGAT activity. The invention further provides diagnostic assays for detecting the presence in a nucleic acid sample of a polymorphism in a DGAT gene that is associated with a condition relating to DGAT activity, and for detecting a propensity to develop a condition associated with DGAT activity. The invention further provides treatment methods.
申请公布号
WO0204682(A3)
申请公布日期
2003.03.27
申请号
WO2001US21915
申请日期
2001.07.10
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;LUDWIG, ERWIN, H.;FARESE, ROBERT, V.;INNERARITY, THOMAS, L.;CASES, SYLVAINE