发明名称 |
ANTAGONISTS OF THE ONCOGENIC ACTIVITY OF THE PROTEIN MDM2, AND USE THEREOF IN THE TREATMENT OF CANCERS |
摘要 |
The present invention relates to the utilization of a compound capable of antagonizing at least partially the oncogenic activity of the protein Mdm2 for the preparation of a pharmaceutical composition intended more particularly to a treatment of cancers with no p53 context. It further relates to the viral vector comprising a nucleic acid sequence coding for a compound capable of inhibiting at least partially the oncogenic activity of the protein Mdm2, and to a corresponding pharmaceutical composition. |
申请公布号 |
US2003060432(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
US19980029327 |
申请日期 |
1998.03.23 |
申请人 |
TOCQUE BRUNO;WASYLYK BOHDAN;DUBS-POTERSZMAN MARIE-CHRISTINE |
发明人 |
TOCQUE BRUNO;WASYLYK BOHDAN;DUBS-POTERSZMAN MARIE-CHRISTINE |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K45/00;A61P35/00;C07K14/47;C07K14/82;C07K16/00;C07K16/32;(IPC1-7):A61K48/00;A61K38/17 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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