发明名称 AMINO ACID MODULATED EXTENDED RELEASE DOSAGE FORM
摘要 <p>Disclosed herein is an oral extended release dosage form, such as a tablet, comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extragranular polymer matrix which is more rapidly hydrating than the intragranular polymer. The amino acid is selected for hydropathy characteristics depending on solubility characteristic of the active compound.</p>
申请公布号 WO2003024428(A1) 申请公布日期 2003.03.27
申请号 US2002005416 申请日期 2002.02.20
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