The invention relates to a newly identified tumor suppressor gene, designated DOS (for Deleted in Osteosarcoma and alternatively referred to herein as DOCK 3) which has been cloned from human nd mouse cells. The DOS nucleic acid and protein molecules and their use in the diagnosing and treating disorders characterized by aberrant DOS molecule expression are described.
申请公布号
WO02100876(B1)
申请公布日期
2003.03.27
申请号
WO2002US18507
申请日期
2002.06.10
申请人
THE GENERAL HOSPITAL CORPORATION;YAJNIK, VIJAY;PAULDING, CHARLES;MCCLATCHEY, ANDREA;HABER, DANIEL
发明人
YAJNIK, VIJAY;PAULDING, CHARLES;MCCLATCHEY, ANDREA;HABER, DANIEL