BIFUNCTIONAL CHELATING AGENT FOR ACTINIUM

摘要

The invention concerns a ligand comprising (I) wherein n is an integer from 1 to 5 Y is CO2H or PO3H2T represents −X or −phenyl−X, wherein X represents NO2, NH2, NCS, NHCOCH2−Z, NHCO−W−COCNHS, −NH−Q, −NHCS−Q, −NHCOCH2−Q, or NHCO(CH2)m−Q where Q is a hapten chosen from the group consisting of steroids, enzymes, proteins, monoclonal antibodies, chimeric antibodies, or fragments thereof or any activated linker ready for coupling reaction, W is −(CH2)m− m is an integer from 1 to 10 Z is chloride, bromide or iodine.