A medicine containing as an active ingredient a compound represented by the following formula [wherein X represents a single bond or optionally substituted C<sb>1−6</sb> alkylene; and A represents optionally substituted C<sb>1−6</sb> alkyl, optionally substituted C<sb>6−10</sb> aryl, or a 4− to 10−membered, mono− or bicyclic, unsaturated or partially or wholly saturated, heterocyclic group containing one to four heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur as ring−constituting atoms (the heterocyclic group may be substituted)]. This medicine is for use in enhancing the effect of treatments for cancers the mechanism of action of which is based on a DNA damage. (I)
申请公布号
WO03024950(A1)
申请公布日期
2003.03.27
申请号
WO2002JP09339
申请日期
2002.09.12
申请人
INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC.;MUTO, SUSUMU;KOMUKAI, MASAYUKI;ITAI, AKIKO