发明名称 COUMARIN DERIVATIVE
摘要 A medicine containing as an active ingredient a compound represented by the following formula [wherein X represents a single bond or optionally substituted C<sb>1−6</sb> alkylene; and A represents optionally substituted C<sb>1−6</sb> alkyl, optionally substituted C<sb>6−10</sb> aryl, or a 4− to 10−membered, mono− or bicyclic, unsaturated or partially or wholly saturated, heterocyclic group containing one to four heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur as ring−constituting atoms (the heterocyclic group may be substituted)]. This medicine is for use in enhancing the effect of treatments for cancers the mechanism of action of which is based on a DNA damage. (I)
申请公布号 WO03024950(A1) 申请公布日期 2003.03.27
申请号 WO2002JP09339 申请日期 2002.09.12
申请人 INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC.;MUTO, SUSUMU;KOMUKAI, MASAYUKI;ITAI, AKIKO 发明人 MUTO, SUSUMU;KOMUKAI, MASAYUKI;ITAI, AKIKO
分类号 A61K31/282;A61K31/37;A61K31/381;A61K31/382;A61K31/385;A61K31/407;A61K31/4433;A61K31/675;A61K31/704;A61K31/7064;A61K33/24;A61K45/06;A61P35/00;A61P43/00;C07D311/16;C07D405/12;C07D407/12;C07D409/12;(IPC1-7):C07D311/16;A61K31/443;A61K31/706 主分类号 A61K31/282
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