| 发明名称 |
COMPOUNDS ACTIVE IN NOVEL SITE ON RECEPTOR-REGULATING CALCIUM CHANNELS AND USED FOR TREATMENT OF NEUROLOGICAL DISTURBANCES AND DISEASES |
| 摘要 |
FIELD: medicine. SUBSTANCE: invention relates to method of screening the therapeutical useful compound eliciting active as non-competitive antagonist of receptor-regulated calcium channel. Proposed method ensures to detect novel compounds and enhance effectiveness of treatment due to reduction of numbers of by-side effects. Invention can be used as neuroprotective, anticonvulsant agents and tranquilizers. EFFECT: valuable medicinal properties of compounds. 18 cl, 2 tbl
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| 申请公布号 |
RU2201224(C2) |
申请公布日期 |
2003.03.27 |
| 申请号 |
RU19960118132 |
申请日期 |
1994.10.26 |
| 申请人 |
EHN-PI-EHS FARMAS'JUTIKALZ, INK. |
发明人 |
MJULLER ALAN L.;VAN VAGENEN BREHDFORD S.;DELMAR EHRIK G.;BALANDRIN MANUEL' F.;MO SKOTT T.;ARTMAN LINDA D.;BARMOR ROBERT M. |
| 分类号 |
A61K31/405;A61K31/135;A61K31/136;A61K31/137;A61K31/138;A61K31/14;A61K31/165;A61K31/17;A61K31/295;A61K31/381;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/4409;A61K31/4462;A61K31/4465;A61K45/00;A61P9/10;A61P9/12;A61P21/02;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/22;A61P25/28;A61P43/00;C07C211/27;C07C211/29;C07C217/62;C07C233/22;C07C235/34;C07C237/22;C07C279/12;C07D209/18;G01N33/53;G01N33/566;(IPC1-7):A61K31/137 |
主分类号 |
A61K31/405 |
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