SUBSTITUTED BENZOIC ACID DERIVATIVES HAVING NF-KB INHIBITINGACTION

摘要

Substituted benzoic acid derivatives represented by the general formula ( ) and exhibiting NF-.kappa.B inhibiting activity: ( ) ( ) ( ) wherein R3, R4, and R5 are each independently hydrogen, C1-6 alkyl, or C1-6 alkoxy; R9 and R10 are each independently hydrogen, C1-6 alkyl, or C2-11 acyl; R2 is an optionally substituted aromatic hydrocarbon group or an optionally substituted heterocyclic group; and X is carboxyl which may be converted into an ester or an amide.