发明名称 |
EXPRESSION OF HUMAN ESTROGEN RECEPTORS IN TRANSGENIC MICE |
摘要 |
The present invention relates to improved compositions and methods for assaying the efficacy of novel drugs functioning either as agonists or antagonists at nuclear receptors. In particular, the invention provides transgenic non-human animals comprising a human steroid hormone receptor gene operably linked to a promoter which directs expression of the steroid hormone receptor gene in an epithelial cell of the non-human animals.
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申请公布号 |
US2003056230(A1) |
申请公布日期 |
2003.03.20 |
申请号 |
US19990365614 |
申请日期 |
1999.08.02 |
申请人 |
ARBEIT JEFFREY M.;KUSHNER PETER J.;UHT ROSALIE M..;ANDEREGG BIRGIT |
发明人 |
ARBEIT JEFFREY M.;KUSHNER PETER J.;UHT ROSALIE M..;ANDEREGG BIRGIT |
分类号 |
A01K67/027;C12N15/85;(IPC1-7):G01N33/00;A01K67/00;C12N15/63 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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