发明名称 INHIBITION BY 3-DEOXYFLAVONOIDS OF T-LYMPHOCYTE ACTIVATION AND THERAPIES RELATED THERETO
摘要 3-Deoxyflavonoid compounds and methods for inhibiting T-cell activity and treating diseases and disorders (e.g., autoimmune disorders, inflammatory disorders, diabetes, ALS, MS, rheumatoid arthritis, etc.). In some cases the efficacy and/or duration of action of luteolin and/or other 3-deoxyflavonoid compounds may be increased by administering such compounds along with Rutin, a Rutin congenor and/or a Rutin derivative. Also, in some cases, first pass metabolism of luteolin or other 3-deoxyflavonoids may be avoided by administering such compounds by parenteral routes (e.g., sublingual, buccal, intranasal, injection, etc.).
申请公布号 WO03022994(A2) 申请公布日期 2003.03.20
申请号 WO2002US28348 申请日期 2002.09.06
申请人 SYNORX, INC. 发明人 LAHEY, THOMAS, P.;RAJADHYAKSHA, V., J.
分类号 A61K31/352;A61K31/353;A61K31/36;A61K31/661;A61K31/7048;A61P3/10;A61P21/00;A61P37/06;C07D311/30;C07D311/32;C07D311/36;C07D407/04;C07D493/04;C07F9/655 主分类号 A61K31/352
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