发明名称 |
3-(4,5,6,7-TETRAHYDROINDOL-2-YLMETHYLIDIENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS |
摘要 |
The present invention relates to 3-(4,5,6,7-tetrahydroindol-2-ylmethylidene)-2-indolinone derivatives of formula I, wherein R1 R4 are defined herein, that inhibit kinases, in particular Src kinase, Pharmaceutical compositions comprising these compounds, methods of treating diseases mediated by kinase utilizing pharmaceutical compositions comprising these compounds, and methods of preparing them are also disclosed.
|
申请公布号 |
WO03022815(A1) |
申请公布日期 |
2003.03.20 |
申请号 |
WO2002US25974 |
申请日期 |
2002.09.10 |
申请人 |
LIANG, CONGXIN;GUAN, HUIPING;TANG, PENG, CHO;BLAKE, ROBERT, A. |
发明人 |
LIANG, CONGXIN;GUAN, HUIPING;TANG, PENG, CHO;BLAKE, ROBERT, A. |
分类号 |
C07D295/04;A61K31/404;A61K31/454;A61K31/495;A61K31/496;A61K31/5377;A61K31/55;A61K31/675;A61P35/00;A61P43/00;C07D209/34;C07D295/14;C07D295/16;C07D401/12;C07D401/14;C07D403/06;C07D403/14;(IPC1-7):C07D209/34;C07D295/02;C07D295/18;C07D295/08;A61K31/40;A61K31/445;A61K31/535 |
主分类号 |
C07D295/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|