发明名称 |
Method for generating libraries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
摘要 |
A method of producing libraries of genes encoding antigen-combining molecules or antibodies is described. In addition, a method of producing antigen-combining molecules which does not require an in vivo procedure is described. Vectors useful in the present method and antigen-combining molecules produced by the method are discussed. The antigen-combining molecules are useful for the detection, quantitation, purification and neutralization of antigens, as well as for diagnostic, therapeutic and prophylactic purposes.
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申请公布号 |
US2003054001(A1) |
申请公布日期 |
2003.03.20 |
申请号 |
US20010798720 |
申请日期 |
2001.03.02 |
申请人 |
WIGLER MICHAEL H.;SORGE JOSEPH A. |
发明人 |
WIGLER MICHAEL H.;SORGE JOSEPH A. |
分类号 |
A61K38/00;C07K16/00;C12N1/21;C12N15/10;C12N15/13;C12Q1/68;(IPC1-7):C12Q1/68;G01N33/53;G01N33/567;A61K39/395;C12N5/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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