发明名称 ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALISED AUXILIARY ARM
摘要 The invention relates in particular to pseudodipeptides which are derived from functionalised aminoacids and which comprise fatty acid chains that are fixed on the amine functions of the pseudodipeptides in amide form, one of the ends of said pseudodipeptides having a functionalised auxiliary arm and the other end being a neutral or charged acid group. The inventive compounds have immunomodulatory properties when used as adjuvants. The inventive compounds can also be grafted onto an antigen in order to modulate the immune response or grafted onto a pharmacophore in order to improve its therapeutic action or its targeting. Finally, the inventive compounds can therefore be used in human and veterinary medicine as immunizing agents and as diagnostic tools.
申请公布号 LV12886(B) 申请公布日期 2003.03.20
申请号 LV20020000118 申请日期 2002.06.21
申请人 OM PHARMA 发明人 BAUER,JACQUES;MARTIN,OLIVIER, RICHARD;RODRIGUEZ,SYLVAIN
分类号 C07H19/06;A61K31/221;A61K31/23;A61K31/661;A61K38/00;A61K38/04;A61K38/36;A61K39/008;A61K39/385;A61K39/39;A61K47/48;A61P7/00;A61P31/12;A61P33/02;A61P37/02;A61P37/04;A61P37/06;A61P43/00;C07C237/10;C07C237/12;C07C237/22;C07C319/20;C07C323/60;C07D237/22;C07F9/09;C07K5/04;(IPC1-7):C07C237/22;A61K31/60 主分类号 C07H19/06
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