| 发明名称 |
HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE CLYCOPROTEIN MUTANTS AND USES THEREOF |
| 摘要 |
<p>This invention provides stable HIV-1 pre-fusion envelope glycoprotein trimer ic complexes. This invention also provides related polypeptides and composition s comprising pharmaceutically acceptable particles and the trimeric complexes operably affixed thereto. This invention further provides related nucleic acids, vectors, host cells, compositions, production methods, and prophylact ic and therapeutic methods.</p> |
| 申请公布号 |
CA2459426(A1) |
申请公布日期 |
2003.03.20 |
| 申请号 |
CA20022459426 |
申请日期 |
2002.09.06 |
| 申请人 |
PROGENICS PHARMACEUTICALS, INC.;CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
GARDNER, JASON;SANDERS, ROGIER;MADDON, PAUL J.;OLSON, WILLIAM C.;BINLEY, JAMES M.;MOORE, JOHN P.;LU, MIN;SCHULKE, NORBERT |
| 分类号 |
C12N15/09;A61K9/127;A61K38/00;A61K38/16;A61K39/00;A61K39/12;A61K39/21;A61K39/39;A61K47/48;A61P31/18;C07K;C07K14/16;C07K16/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/48;C12P21/02;(IPC1-7):C12N15/48 |
主分类号 |
C12N15/09 |
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