| 发明名称 |
PSEUDOMONAS EXOTOXIN A-LIKE CHIMERIC IMMUNOGENS FOR ELICITING A SECRETORY IGA-MEDIATED IMMUNE RESPONSE |
| 摘要 |
This invention provides methods of eliciting a secretry IgA-mediated immune response in a subject by administering a Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Compositions comprising secretory IgA antibodies that specifically recognize an epitope of HIV-1 also are provided
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| 申请公布号 |
US2003054012(A1) |
申请公布日期 |
2003.03.20 |
| 申请号 |
US20000462713 |
申请日期 |
2000.05.12 |
| 申请人 |
FITZGERALD DAVID J.;MRSNY RANDALL J. |
发明人 |
FITZGERALD DAVID J.;MRSNY RANDALL J. |
| 分类号 |
A61K39/00;C07K14/16;C07K14/21;C07K16/10;(IPC1-7):A61K39/02;C12Q1/70 |
主分类号 |
A61K39/00 |
| 代理机构 |
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