| 摘要 |
<p>The invention concerns an automatic apparatus for synthesis of organic molecules, in particular in solid phase, in accordance with combinative or parallel synthesis protocols. Said apparatus is characterized in that it mainly comprises: several synthesis modules (2) including each five reactors (3) temperature-controlled by heating and cooling means, a container (6) forming a secondary mixing chamber and whereof the capacity corresponds to at least the sum of capacities of the reactors (3) of a module (2), being associated with each module and an additional container (7) being provided, forming a main mixing chamber whereof the capacity corresponds to at least the sum of capacities of the various secondary mixing chambers (6), and at least a circuit for transferring the contents of the reactors (3) to the container (6) associated with a specific synthesis module (2) and/or to the container (7) and for the controlled distribution of the content of one or more containers (6) and/or of the content of the container (7) between the containers (6) or the reactors (3), and at least a supply or discharge circuit connected in particular to the different inlets/outlets of the reactors (3) and of the containers (6, 7) and, finally, a ramified system for managing and controlling the flow and the distribution of the fluids in said circuits and the temperature and stirring in the chambers of the reactors (3).</p> |
