LYMPHOCYTIC ACTIVATION INHIBITOR AND REMEDIAL AGENT FOR AUTOIMMUNE DISEASE

摘要

A lymphocytic activation inhibitor and a remedial agent for autoimmune diseases which each comprises as an active ingredient a sulfonamide derivative or sulfonic ester derivative represented by the general formula I: I [wherein ring A means an optionally substituted, mono- or bicyclic aromatic ring ring B means an optionally substituted, 6-membered, cyclic unsaturated hydrocarbon or an unsaturated 6-membered heterocycle containing one nitrogen atom ring C means an optionally substituted 5-membered heterocycle containing one or two nitrogen atoms W means a single bond or -CH=CH- X means -NR1- or oxygen Y means carbon or nitrogen Z means -NR2- or nitrogen and R1 and R2 are the same or different and each means hydrogen or lower alkyl], a pharmacologically acceptable salt thereof, or a hydrate of any of these.