发明名称 |
Methods for encapsulating plasmids in lipid bilayers |
摘要 |
Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, fully encapsulate the plasmid and are serum-stable.
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申请公布号 |
US6534484(B1) |
申请公布日期 |
2003.03.18 |
申请号 |
US19990436933 |
申请日期 |
1999.11.08 |
申请人 |
INEX PHARMACEUTICALS CORP. |
发明人 |
WHEELER JEFFERY J.;HOPE MICHAEL;CULLIS PIETER R.;BALLY MARCEL B. |
分类号 |
A61K9/127;C12N15/88;(IPC1-7):A01N43/04 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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