| 摘要 |
The invention relates to a compound having the formula (I)whereinR1 is cyclopentyl, cyclohexyl or a branched (3-4C)alkyl;R2 is cyclohexyl or phenyl;R3 is H or methyl; andA is an unsubstituted saturated 4, 5 or 6-membered ring;or a pharmaceutically acceptable salt thereof.The compounds of the invention have anticoagulant activity and can be used in treating or preventing thrombin-mediated and thrombin-associated diseases.
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