发明名称 PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS
摘要 The present invention provides a compound of the formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R9, R10, A and B are as defined in the specification. The present invention also provides pharmaceutical compositions containing the compound of this invention, and methods of treatment using the compound of this invention. Th e invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
申请公布号 CA2457861(A1) 申请公布日期 2003.03.13
申请号 CA20022457861 申请日期 2002.08.28
申请人 SCHERING CORPORATION 发明人 PALANI, ANANDAN;MILLER, MICHAEL W.;SCOTT, JACK D.
分类号 C07D401/04;A61K31/4545;A61K31/506;A61K45/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P31/18;A61P37/06;A61P43/00;C07D401/14;(IPC1-7):C07D401/04;A61K31/435 主分类号 C07D401/04
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