发明名称 |
Clostridial toxin derivatives able to modify peripheral sensory afferent functions |
摘要 |
The invention relates to an agent specific for peripheral sensory afferents. The agent may inhibit the transmission of signals between a primary sensory afferent and a projection neutron by controlling the release of at least one neurotransmitter or neuromodulator from the primary sensory afferent. The agent may be used in or as a pharmaceutical for the treatment of pain, particularly chronic pain.
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申请公布号 |
US2003049264(A1) |
申请公布日期 |
2003.03.13 |
申请号 |
US20020150262 |
申请日期 |
2002.05.20 |
申请人 |
THE SPEYWOOD LABORATORY LTD. |
发明人 |
FOSTER KEITH ALAN;DUGGAN MICHAEL JOHN;SHONE CLIFFORD CHARLES |
分类号 |
C12N15/09;A61K35/74;A61K38/00;A61K38/16;A61K38/22;A61K38/46;A61K38/48;A61K39/395;A61K47/48;A61P25/00;A61P25/04;C07K14/33;C07K14/48;C07K19/00;C12N9/52;C12N15/31;C12N15/62;C12P21/02;(IPC1-7):A61K39/08;C12P21/06;C12P21/04;A61K39/40;A61K39/44;C07K14/00;A61K39/42;C07K1/00;C07K17/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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