发明名称 |
COMBINATION HIV THERAPY INCLUDING CAMPTOTHECIN |
摘要 |
A method is provided for treating HIV infection using a combination therapy which includes a compound selected from the group consisting of 20(S)-camptothecin, analog of 20(S)-camptothecin, derivative of 20(S)-camptothecin, precursor of 20(S)-camptothecin and metabolite of 20(S)-camptothecin, in combination with a cocktail of antiretroviral drugs such as nucleoside reverse transcriptase inhibitors, non-nucleoside HIV reverse transcriptase inhibitors, protease inhibitors, fusion inhibitors and integrase inhibitors. The method comprises administering highly active antiretroviral therapy (HAART); and co-administering to the HIV-infected host therapeutically effective amount of a compound selected from the group consisting of 20(S)-camptothecin, analog of 20(S)-camptothecin, derivative of 20(S)-camptothecin, precursor of 20(S)-camptothecin and metabolite of 20(S)-camptothecin. |
申请公布号 |
WO0200168(A3) |
申请公布日期 |
2003.03.13 |
申请号 |
WO2001US19863 |
申请日期 |
2001.06.20 |
申请人 |
SUPERGEN, INC.;SCHOCHETMAN, GERALD;CHANG, LUCY;RUBINFELD, JOSEPH |
发明人 |
SCHOCHETMAN, GERALD;CHANG, LUCY;RUBINFELD, JOSEPH |
分类号 |
A61K31/70;A61K45/06;A61P31/18 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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