发明名称 DNA encoding a human dopamine D1 receptor and uses thereof
摘要 This invention provides isolated nucleic acid molecules encoding a human dopamine D1 receptor, isolated proteins which are human dopamine D1 receptor, vectors comprising isolated nucleic acid molecules encoding a human dopamine D1 receptor, mammalian cells comprising such vectors, antibodies directed to a human dopamine D1 receptor, nucleic acid probes useful for detecting nucleic acid encoding human dopamine D1 receptor, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human dopamine D1 receptor, pharmaceutical compounds related to human dopamine D1 receptor, and nonhuman transgenic animals which express DNA a normal or a mutant human dopamine D1 receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving a human dopamine D1 receptor.
申请公布号 US2003049794(A1) 申请公布日期 2003.03.13
申请号 US20020277078 申请日期 2002.10.21
申请人 SYNAPTIC PHARMACEUTICAL CORPORATION 发明人 WEINSHANK RICHARD L.;HARTIG PAUL R.
分类号 A61K38/00;C07K14/705;C12N1/21;C12N15/12;C12N15/85;C12Q1/68;G01N33/566;G01N33/94;(IPC1-7):C07K14/705;C07H21/04;C12P21/02;C12N5/06;C12N1/18;C12N15/74 主分类号 A61K38/00
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