发明名称 Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism
摘要 A purification method includes bonding a probe to a target in a sample to form a complex, and separating the sample from the complex to separate in a sequence specific manner the target from the sample. The complex, which is immobilized on a support, is a duplex, triplex or quadruplex formed by Watson-Crick complementary base interaction or by homologous base interaction, provided that when the complex is a duplex and the heteropolymeric probe sequence is antiparallel to the heteropolymeric target sequence, the heteropolymeric probe sequence is bonded to the heteropolymeric target sequence by homologous base interaction, and provided that when the complex is a triplex, the complex is free of recombination proteins. A kit for performing the method includes the support and the probe.
申请公布号 US2003049673(A1) 申请公布日期 2003.03.13
申请号 US20020269229 申请日期 2002.10.11
申请人 INGENEUS CORPORATION 发明人 ATKINSON IAN J.;ERIKSON GLEN H.;DAKSIS JASMINE I.;PICARD PIERRE
分类号 C12Q1/68;(IPC1-7):C12Q1/68;B05D3/00 主分类号 C12Q1/68
代理机构 代理人
主权项
地址
您可能感兴趣的专利