ORAL VACCINES

摘要

This invention features an oral vaccine that includes a multiple-cell organism for use as food for an aquatic animal ( e.g., a fish or a shrimp) to be vaccinated, and a single- cell organism fed to, and as a result, bioencapsulated by, the multiple-cell organism. The single-cell organism has been transformed to express a recombinant antigen that induces an immune response in the aquatic animal and thereby vaccinates the aquatic animal.