发明名称 |
Complexes of alpha-6 integrin subunits with small peptides and methods for treating indications resulting from modulation of integrin-mediated responses by altering signal transduction |
摘要 |
A method for modulating an alpha 6 subunit containing integrin-mediated signal transduction is described. The method involves contacting a cell with an effective integrin modulating amount of an alpha 6 subunit containing integrin-mediated signal transduction pathway modification agent. Preferred agents are peptides having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
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申请公布号 |
US2003050249(A1) |
申请公布日期 |
2003.03.13 |
申请号 |
US20010863837 |
申请日期 |
2001.05.23 |
申请人 |
CLAGETT JAMES A.;LIPANI JOHN;PALMER CRAIG ROBERT |
发明人 |
CLAGETT JAMES A.;LIPANI JOHN;PALMER CRAIG ROBERT |
分类号 |
G01N33/50;A61K38/00;A61K45/00;A61P1/04;A61P7/02;A61P9/10;A61P11/00;A61P11/06;A61P17/06;A61P19/02;A61P19/08;A61P29/00;A61P35/04;A61P43/00;C07K5/083;C07K5/103;C07K14/47;C07K14/705;G01N33/15;(IPC1-7):A61K38/07;A61K31/573 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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地址 |
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