Novel splice variants of the human H4 histamine receptor are described. The splice variants have delections of portions of the N-terminal of the wild type H4 receptor. The splice variants are useful in methods for identifying agonists, inverse agonists or antagonists of histamnie action at the H4 receptor.
申请公布号
WO03020907(A2)
申请公布日期
2003.03.13
申请号
WO2002US27891
申请日期
2002.08.30
申请人
MERCK & CO., INC.;GALLAGHER, MICHAEL, J.;YATES, STEPHEN, L.