RAGWEED ALLERGENS

摘要

A 30 kDa ragweed complete pollen extract disulfide protein allergen has been purified from ragweed pollen. IgE immunoblots with sera of ragweed sensitive patients indicated that the 30 kDa protein is a major allergen. The 30 kDA protein finds use in allergy testing and immunotherapy regimens. In addition to the 30 kDa disulfide protein isolated from complete ragweed pollen, an 8-10 kDa ragweed complete pollen extract disulfide protein and a 30 kDa ragweed defatted pollen extract disulfide protein and fragments, derivatives and homologues thereof are described.